N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP)
NT-proBNP is released in response to myocardial wall stress; quantitative measurement supports cardiac disease screening and helps distinguish cardiac from respiratory causes of dyspnoea in dogs and cats.
Fact Table
| Species | Canine & Feline |
|---|---|
| Biomarker | N-terminal pro-brain natriuretic peptide (NT-proBNP) |
| Method | Fluorescence immunoassay (FICT) |
| Unit | pmol/L |
| Category | Cardiac |
Clinical Context
NT-proBNP is released in response to myocardial wall stress; quantitative measurement supports cardiac disease screening and helps distinguish cardiac from respiratory causes of dyspnoea in dogs and cats.
Interpretation should always combine the quantitative result with the patient's signalment, history, clinical signs, and any other laboratory findings. A single value is rarely diagnostic on its own; serial measurements often provide more useful information.
Reference Range
Reference ranges vary by species, age and laboratory method — always interpret against the kit IFU and your in-house validation.
Related Test Kits
Related Articles
- NT-proBNP in Dogs and Cats: Heart vs Breathing Trouble A coughing dog and fast-breathing cat look alike. NT-proBNP tells whether the cause is heart or lungs — in 10–20 minutes. Here are the cut-offs.
- SDMA and NT-proBNP: Kidney and Heart Markers in Pets A guide to SDMA, cystatin C, NT-proBNP, cPL, CRP, SAA, cortisol and thyroid hormones — reference ranges and how quantitative testing helps.
Manufacturer documentation + clinical literature cited in related articles
2026-09-12
MEDIUM — reference ranges are method-specific
FAQ
What does the N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) test measure?
Migibio's N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) test is a quantitative fluorescence immunoassay (FICT) run on the FIA680/FIA880 analyzer. It is intended as an aid in clinical assessment: NT-proBNP is released in response to myocardial wall stress; quantitative measurement supports cardiac disease screening and helps distinguish cardiac from respiratory causes of dyspnoea in dogs and cats. The exact specimen, sample handling, and reporting units are specified in the kit IFU.
When is NT-proBNP testing most useful?
When heart disease is suspected, before anaesthesia in at-risk patients, or to screen predisposed breeds. Interpret NT-proBNP alongside echocardiography and clinical findings. For dogs and cats, use the result with the clinical history, physical examination, and any other laboratory findings.
Why does this Data Hub not publish a universal reference range?
Reference ranges vary by species, age and laboratory method — always interpret against the kit IFU and your in-house validation.